Another recent publication suggests that MT in M2 occlusions might be safe and efficient, although treatment effects of successful recanalization were not reported. 8 However, recanalization success and respective treatment effects were not considered in the analysis. 9 A recent meta-analysis of RCTs on MT that also enrolled patients with M2 occlusions confirmed improved clinical outcome for patients receiving MT (n=195) versus best medical management (n=322). 3–8 Furthermore, MT has been recently emphasized by an international consensus as an encouraging option for medium and distal occlusions 2 and is now increasingly performed for medium and distal occlusion strokes. 2 Emerging data suggest that MT might also be safe and effective for medium and distal occlusions. 1 However, 24% to 40% of acute ischemic strokes are caused by medium and distal occlusions. Large vessel occlusions are defined as occlusions in the intracranial internal carotid artery (ICA) and the M1 segment of the middle cerebral artery (MCA). Treatment effects of successful recanalization after mechanical thrombectomy (MT) have been evaluated in randomized controlled trials (RCTs) for acute ischemic strokes with large vessel occlusion. Correspondence to Helge Kniep, Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany H.4 Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.3 Department of Neurology, Asklepios Klinik Altona, Hamburg, Hamburg, Germany.2 Radiology, Stanford University School of Medicine, Stanford, California, USA.1 Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.for the German Stroke Registry – Endovascular Treatment (GSR – ET).
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